Alternative (non-P-glycoprotein) mechanisms of drug resistance in non-Hodgkin's lymphoma

被引：8

作者：

Dalton, WS

机构：

[1] H. Lee Moffitt Cancer Center, Tampa, FL 33612

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 1997年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0889-8588(05)70474-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Drug resistance remains a significant obstacle to improving therapeutic outcome following treatment for malignant lymphoma. Eliminating P-glycoprotein as one mechanism of drug resistance may select for alternative, non-P-glycoprotein mechanisms of drug resistance. Understanding these alternative forms of drug resistance is imperative in order to improve therapy for NHL.

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页码：975 / &

页数：13

相关论文

共 39 条

[1]

BECK WT, 1991, MOL CLIN ADV ANTICAN, P151

[2]

BRENT TP, 1986, CANCER RES, V46, P2320

[3]

BURGER H, 1994, LEUKEMIA, V8, P990

[4]

CHEN M, 1995, ONCOL RES, V7, P103

[5] EXPRESSION OF P-GLYCOPROTEIN AND GLUTATHIONE-S-TRANSFERASE IN RECURRENT LYMPHOMAS - THE POSSIBLE ROLE OF EPSTEIN-BARR-VIRUS, IMMUNOPHENOTYPES, AND OTHER PREDISPOSING FACTORS [J].

CHENG, AL ;

SU, IJ ;

CHEN, YC ;

LEE, TC ;

WANG, CH .

JOURNAL OF CLINICAL ONCOLOGY, 1993, 11 (01) :109-115

[6] OVEREXPRESSION OF A TRANSPORTER GENE IN A MULTIDRUG-RESISTANT HUMAN LUNG-CANCER CELL-LINE [J].

COLE, SPC ;

BHARDWAJ, G ;

GERLACH, JH ;

MACKIE, JE ;

GRANT, CE ;

ALMQUIST, KC ;

STEWART, AJ ;

KURZ, EU ;

DUNCAN, AMV ;

DEELEY, RG .

SCIENCE, 1992, 258 (5088) :1650-1654

[7]

Dalton William S., 1994, Current Opinion in Oncology, V6, P595, DOI 10.1097/00001622-199411000-00011

[8] DRUG-RESISTANCE IN MULTIPLE-MYELOMA AND NON-HODGKINS LYMPHOMA - DETECTION OF P-GLYCOPROTEIN AND POTENTIAL CIRCUMVENTION BY ADDITION OF VERAPAMIL TO CHEMOTHERAPY [J].

DALTON, WS ;

GROGAN, TM ;

MELTZER, PS ;

SCHEPER, RJ ;

DURIE, BGM ;

TAYLOR, CW ;

MILLER, TP ;

SALMON, SE .

JOURNAL OF CLINICAL ONCOLOGY, 1989, 7 (04) :415-424

[9] EXPRESSION OF A MULTIDRUG-RESISTANCE GENE IN HUMAN-MALIGNANT LYMPHOMA AND RELATED DISORDERS [J].

DAN, S ;

ESUMI, M ;

SAWADA, U ;

HAYASHI, N ;

UCHIDA, T ;

YAMAZAKI, T ;

ASHIYA, M ;

SATOH, Y ;

OHSHIM, T ;

HORIE, T ;

TSURUO, T ;

SHIKATA, T .

LEUKEMIA RESEARCH, 1991, 15 (12) :1139-1143

[10] THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE [J].

ENDICOTT, JA ;

LING, V .

ANNUAL REVIEW OF BIOCHEMISTRY, 1989, 58 :137-171

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