New chiral phosphinamide catalysts for highly enantioselective reduction of ketones.

被引：53

作者：

Gamble, MP ^{[1
]}

Studley, JR ^{[1
]}

Wills, M ^{[1
]}

机构：

[1] UNIV WARWICK,DEPT CHEM,COVENTRY CV4 7AL,W MIDLANDS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 16期

关键词：

D O I：

10.1016/0040-4039(96)00404-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel class of recoverable and highly stable phosphinamide catalysts for the asymmetric reduction of ketones by borane is described. Enantiomeric excesses of up to 92% have been obtained using 10 mol% of the optimum catalyst. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：2853 / 2856

页数：4

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