Frameshift mutations in Fas, Apaf-1, and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype

被引:56
作者
Yamamoto, H
Gil, J
Schwartz, S
Perucho, M
机构
[1] Burnham Inst, La Jolla, CA 92037 USA
[2] Univ Barcelona, Dept Ciencies Fisiol 2, Unitat Bioquim, Lhospitalet De Llobregat, Spain
[3] Ctr Invest Bioquim & Biol Mol Vall Dhebron, Barcelona, Spain
关键词
D O I
10.1038/sj.cdd.4400651
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:238 / 239
页数:2
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共 20 条
  • [1] Death pathway genes Fas (Apo-1/CD95) and Bik (Nbk) show no mutations in colorectal carcinomas
    Abdel-Rahman, WM
    Arends, MJ
    Wyllie, AH
    Morris, RG
    Ramadan, ME
    [J]. CELL DEATH AND DIFFERENTIATION, 1999, 6 (05) : 387 - 388
  • [2] Death receptors: Signaling and modulation
    Ashkenazi, A
    Dixit, VM
    [J]. SCIENCE, 1998, 281 (5381) : 1305 - 1308
  • [3] Bcl10 mutations in malignancy
    Dyer, MJS
    [J]. BRITISH JOURNAL OF CANCER, 1999, 80 (10) : 1491 - 1491
  • [4] A GENETIC MODEL FOR COLORECTAL TUMORIGENESIS
    FEARON, ER
    VOGELSTEIN, B
    [J]. CELL, 1990, 61 (05) : 759 - 767
  • [5] Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
    Hu, YM
    Benedict, MA
    Ding, LY
    Núñez, G
    [J]. EMBO JOURNAL, 1999, 18 (13) : 3586 - 3595
  • [6] UBIQUITOUS SOMATIC MUTATIONS IN SIMPLE REPEATED SEQUENCES REVEAL A NEW MECHANISM FOR COLONIC CARCINOGENESIS
    IONOV, Y
    PEINADO, MA
    MALKHOSYAN, S
    SHIBATA, D
    PERUCHO, M
    [J]. NATURE, 1993, 363 (6429) : 558 - 561
  • [7] Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer
    Lee, SH
    Shin, MS
    Park, WS
    Kim, SY
    Kim, HS
    Han, JY
    Park, GS
    Dong, SM
    Pi, JH
    Kim, CS
    Kim, SH
    Lee, JY
    Yoo, NJ
    [J]. ONCOGENE, 1999, 18 (25) : 3754 - 3760
  • [8] Lee SH, 1999, CANCER RES, V59, P3068
  • [9] Frameshift mutator mutations
    Malkhosyan, S
    Rampino, N
    Yamamoto, H
    Perucho, M
    [J]. NATURE, 1996, 382 (6591) : 499 - 500
  • [10] INACTIVATION OF THE TYPE-II TGF-BETA RECEPTOR IN COLON-CANCER CELLS WITH MICROSATELLITE INSTABILITY
    MARKOWITZ, S
    WANG, J
    MYEROFF, L
    PARSONS, R
    SUN, LZ
    LUTTERBAUGH, J
    FAN, RS
    ZBOROWSKA, E
    KINZLER, KW
    VOGELSTEIN, B
    BRATTAIN, M
    WILLSON, JKV
    [J]. SCIENCE, 1995, 268 (5215) : 1336 - 1338