Chronic Thromboembolic Pulmonary Hypertension

被引：42

作者：

Auger, William R. ^{[1
]}

Fedullo, Peter F. ^{[2
]}

机构：

[1] Univ Calif San Diego, Div Pulm & Crit Care Med, La Jolla, CA 92037 USA

[2] Univ Calif San Diego, Div Pulm & Crit Care Med, San Diego, CA 92103 USA

来源：

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE | 2009年 / 30卷 / 04期

关键词：

Pulmonary hypertension; chronic thromboemboli; pulmonary thromboendarterectomy; pulmonary vasodilator therapy; TERM-FOLLOW-UP; SURGICAL-MANAGEMENT; CIRCULATORY ARREST; INTRAVENOUS EPOPROSTENOL; TECHNICAL ADVANCES; GENE-EXPRESSION; SCAN FINDINGS; RISK-FACTORS; THROMBOENDARTERECTOMY; ENDARTERECTOMY;

D O I：

10.1055/s-0029-1233316

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The last 4 decades have witnessed dramatic changes In the treatment of patients with pulmonary hypertension. And with the advances in cardiothoracic surgical techniques, selected patients with chronic thromboembolic pulmonary hypertension (CTEPH) are afforded a Surgical remedy for their disease. In the vast majority of these patients, Surgical endarterectomy of chronic thromboemboli from the pulmonary vascular bed effectively treats even severe Pulmonary hypertension, and as a result, the debilitating symptoms of right heart dysfunction. This article reviews the natural history of chronic thromboembolic disease and outline a Suggested diagnostic approach to determine whether a patient with chronic thromboembolic disease might be an appropriate surgical candidate. Pulmonary thromboendarterectomy surgery, and the growing information Oil the use of pharmacotherapy in inoperable CTEPH, are also reviewed.

引用

页码：471 / 483

页数：13

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