Comparative Study of Antibiofilm Activity of Copper Oxide and Iron Oxide Nanoparticles Against Multidrug Resistant Biofilm Forming Uropathogens

被引:105
作者
Agarwala, Munin [1 ]
Choudhury, Bula [2 ]
Yadav, R. N. S. [1 ]
机构
[1] Dibrugarh Univ, Ctr Studies Biotechnol, Dibrugarh 786004, Assam, India
[2] IIT Guwahati, Gauhati 781039, Assam, India
关键词
Biofilm; Uropathogens; Nanoparticles; CuO; Fe2O3;
D O I
10.1007/s12088-014-0462-z
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
The effectiveness of the metal oxide nanoparticles viz. CuO and Fe2O3 as antibacterial agents against multidrug resistant biofilm forming bacteria was evaluated. CuO nanoparticles were also experimented for antibiofilm and time kill assay. The CuO displayed maximum antibacterial activity with zone of inhibition of (22 +/- A 1) mm against methicillin resistant Staphylococcus aureus (MRSA) followed by Escherichia coli (18 +/- A 1) mm. The Fe2O3 showed the zone of inhibition against MRSA of (14 +/- A 1) mm followed by E. coli (12 +/- A 1) mm. CuO proved to be more toxic than Fe2O3 nanoparticles showing significantly high antibacterial activity and found to possess dose dependent antibiofilm properties.
引用
收藏
页码:365 / 368
页数:4
相关论文
共 11 条
[1]
Copper, 2009, CURR CHEM BIOL, V3, P272, DOI DOI 10.2174/187231309789054887
[2]
Das A, 2012, NUTRA FOODS, V12, P83
[3]
Evolution of Resistance to Quorum-Sensing Inhibitors [J].
Kalia, Vipin C. ;
Wood, Thomas K. ;
Kumar, Prasun .
MICROBIAL ECOLOGY, 2014, 68 (01) :13-23
[4]
Quorum sensing inhibitors: An overview [J].
Kalia, Vipin Chandra .
BIOTECHNOLOGY ADVANCES, 2013, 31 (02) :224-245
[5]
Kalia Vipin Chandra, 2011, Open Microbiol J, V5, P1, DOI 10.2174/1874285801105010001
[6]
Quenching the quorum sensing system: potential antibacterial drug targets [J].
Kalia, Vipin Chandra ;
Purohit, Hemant J. .
CRITICAL REVIEWS IN MICROBIOLOGY, 2011, 37 (02) :121-140
[7]
Preparation and antibacterial activities of polyaniline/Cu0.05Zn0.95O nanocomposites [J].
Liang, Xiaoxi ;
Sun, Mengxi ;
Li, Liangchao ;
Qiao, Ru ;
Chen, Keyu ;
Xiao, Qiushi ;
Xu, Feng .
DALTON TRANSACTIONS, 2012, 41 (09) :2804-2811
[8]
Phytoextracts-Synthesized Silver Nanoparticles Inhibit Bacterial Fish Pathogen Aeromonas hydrophila [J].
Mahanty, Arabinda ;
Mishra, Snehasish ;
Bosu, Ranadhir ;
Maurya, U. K. ;
Netam, Surya Prakash ;
Sarkar, Biplab .
INDIAN JOURNAL OF MICROBIOLOGY, 2013, 53 (04) :438-446
[9]
Merritt Judith H, 2005, Curr Protoc Microbiol, VChapter 1, DOI 10.1002/9780471729259.mc01b01s00
[10]
Ravikumar S., 2012, Asian Pacific Journal of Tropical Biomedicine, V2, P92, DOI 10.1016/S2221-1691(11)60199-8