High-frequency cranial electrostimulation (CES) in patients with probable Alzheimer's disease

被引:13
作者
Scherder, EJA
van Tol, MJ
Swaab, DF
机构
[1] Free Univ Amsterdam, Dept Clin Neuropsychol, NL-1081 BT Amsterdam, Netherlands
[2] Univ Groningen, Inst Human Movement Sci, Groningen, Netherlands
[3] Netherlands Inst Brain Res, Amsterdam, Netherlands
关键词
cranial electrostimulation; Alzheimer's disease; cognition; affective behavior; independent functioning;
D O I
10.1097/01.phm.0000223221.17301.50
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
In a previous study, low-frequency cranial electrostimulation did not improve cognition and (affective) behavior in patients with probable Alzheimer's disease. In the present study, 2 1 Alzheimer's disease patients, divided into an experimental (n = 1 1) and a control group (n = 10), were treated for 30 mins/day, 5 days/wk, for 6 wks with high-frequency cranial electrostimulation. Similar to the previous study, no improvements on cognition and (affective) behavior were found.
引用
收藏
页码:614 / 618
页数:5
相关论文
共 28 条
[1]  
[Anonymous], GRONINGER INTELLIGEN
[2]   AN INVENTORY FOR MEASURING DEPRESSION [J].
BECK, AT ;
ERBAUGH, J ;
WARD, CH ;
MOCK, J ;
MENDELSOHN, M .
ARCHIVES OF GENERAL PSYCHIATRY, 1961, 4 (06) :561-&
[3]  
Derogatis LR, 1977, SCL90 ADM SCORING PR
[4]   Alzheimer's disease: more than a 'cholinergic disorder' - evidence that cholinergic-monoaminergic interactions contribute to EEG slowing and dementia [J].
Dringenberg, HC .
BEHAVIOURAL BRAIN RESEARCH, 2000, 115 (02) :235-249
[5]   MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].
FOLSTEIN, MF ;
FOLSTEIN, SE ;
MCHUGH, PR .
JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198
[6]   The PDAPP mouse model of Alzheimer's disease: Locus coeruleus neuronal shrinkage [J].
German, DC ;
Nelson, O ;
Liang, F ;
Liang, CL ;
Games, D .
JOURNAL OF COMPARATIVE NEUROLOGY, 2005, 492 (04) :469-476
[7]   Electrical stimulation of the dorsal and median raphe nuclei increases extracellular noradrenaline in rat hippocampus:: Evidence for a 5-HT-independent mechanism [J].
Hajós-Korcsok, É ;
Sharp, T .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2002, 71 (04) :807-813
[8]  
Hozumi S, 1996, INT J NEUROSCI, V88, P1
[9]   AFFERENTS TO THE BASAL FOREBRAIN CHOLINERGIC CELL AREA FROM PONTOMESENCEPHALIC CATECHOLAMINE, SEROTONIN, AND ACETYLCHOLINE NEURONS [J].
JONES, BE ;
CUELLO, AC .
NEUROSCIENCE, 1989, 31 (01) :37-61
[10]   Brainstem neural mechanisms of sleep and wakefulness [J].
Kayama, Y ;
Koyama, Y .
EUROPEAN UROLOGY, 1998, 33 :12-15