Focal transmantle dysplasia: A specific malformation of cortical development

被引：136

作者：

Barkovich, AJ

Kuzniecky, RI

Bollen, AW

Grant, PE

机构：

[1] UNIV ALABAMA,DEPT NEUROL,EPILEPSY SERV,BIRMINGHAM,AL 35294

[2] UNIV CALIF SAN FRANCISCO,DEPT PATHOL,DIV NEUROPATHOL,SAN FRANCISCO,CA

来源：

NEUROLOGY | 1997年 / 49卷 / 04期

关键词：

D O I：

10.1212/WNL.49.4.1148

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report 18 patients who presented prior to age 20 years with epilepsy or fixed neurologic deficits. MRI showed signal abnormality extending from the cortex to the superolateral wall of the lateral ventricle. Histology showed cortical disorganization, neuronal cytomegaly, balloon cells, indistinct cortical gray matter-white matter junctions, and variable accompanying astrogliosis. We propose that this transmantle dysplasia is a specific anomaly resulting from abnormal stem cell development.

引用

页码：1148 / 1152

页数：5

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