Treatment of stable chronic obstructive pulmonary disease

被引:62
作者
Rennard, SI [1 ]
机构
[1] Univ Nebraska, Med Ctr, Pulm & Crit Care Med Sect, Omaha, NE 68198 USA
关键词
D O I
10.1016/S0140-6736(04)16941-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic obstructive pulmonary disease (COPD) is a readily diagnosable disorder that responds to treatment. Smoking cessation can reduce symptoms and prevent progression of disease. Bronchodilator therapy is key in improvement of lung function. Three classes of bronchodilators-beta agonists, anticholinergics, and theophylline-re available and can be used individually or in combination. Inhaled glucocorticoids can also improve airflow and can be combined with bronchodilators. Inhaled glucocorticoids, in addition, might reduce exacerbation frequency and severity as might some bronchodilators. Effective use of pharmacotherapy in COPD needs integration with a rehabilitation programme and successful treatment of co-morbidities, including depression and anxiety. Treatment for stable COPD can improve the function and quality of life of many patients, could reduce admissions to hospital, and has been suggested to improve survival.
引用
收藏
页码:791 / 802
页数:12
相关论文
共 136 条
[1]  
AbdelLatif AA, 1996, P SOC EXP BIOL MED, V211, P163
[2]  
ALBERT RK, 1980, ANN INTERN MED, V92, P753, DOI 10.7326/0003-4819-92-6-753
[3]  
Altose MD, 2000, NEW ENGL J MED, V343, P1902
[4]  
[Anonymous], 1991, JAMA, V266, P3133
[5]  
[Anonymous], [No title captured]
[6]   ANTIBIOTIC-THERAPY IN EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY-DISEASE [J].
ANTHONISEN, NR ;
MANFREDA, J ;
WARREN, CPW ;
HERSHFIELD, ES ;
HARDING, GKM ;
NELSON, NA .
ANNALS OF INTERNAL MEDICINE, 1987, 106 (02) :196-204
[7]   Smoking and lung function of lung health study participants after 11 years [J].
Anthonisen, NR ;
Connett, JE ;
Murray, RP .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 166 (05) :675-679
[8]   EFFECTS OF SMOKING INTERVENTION AND THE USE OF AN INHALED ANTICHOLINERGIC BRONCHODILATOR ON THE RATE OF DECLINE OF FEV(1) - THE LUNG HEALTH STUDY [J].
ANTHONISEN, NR ;
CONNETT, JE ;
KILEY, JP ;
ALTOSE, MD ;
BAILEY, WC ;
BUIST, AS ;
CONWAY, WA ;
ENRIGHT, PL ;
KANNER, RE ;
OHARA, P ;
OWENS, GR ;
SCANLON, PD ;
TASHKIN, DP ;
WISE, RA .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 272 (19) :1497-1505
[9]  
ARGYROPOULOU P, 1993, RESPIRATION, V60, P216
[10]   Theophylline - New perspectives for an old drug [J].
Barnes, PJ .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2003, 167 (06) :813-818