Opportunities for nanotechnology-based innovation in tissue proteomics

被引：25

作者：

Geho, DH

Lahar, N

Ferrari, M

Petricoin, EF

Liotta, LA

机构：

[1] NCI, US FDA, NCI,Clin Proteom Program, Lab Pathol,Ctr Canc Res, Bethesda, MD 20892 USA

[2] US FDA, NCI, Clin Proteom Program, Ctr Biol Evaluat & Res, Bethesda, MD USA

[3] Ohio State Univ, Dept Internal Med, Div Haematol & Oncol, Columbus, OH 43210 USA

[4] Ohio State Univ, Dorothy M Davis Heart & Lung Res Inst, Columbus, OH 43210 USA

来源：

BIOMEDICAL MICRODEVICES | 2004年 / 6卷 / 03期

关键词：

tissue proteomics; nanotechnology; protein microarrays; mass spectrometry;

D O I：

10.1023/B:BMMD.0000042053.51016.b4

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Within this review we discuss two methodologies used in tissue proteomics, namely mass-spectrometry (MS)-based protein pattern diagnostics and protein microarrays. Further, we describe current goals within the field of tissue proteomics and suggest points of departure for designing nanotechnology-based tools that will enhance the role of molecularly based diagnostics and therapeutics development in clinical medicine.

引用

页码：231 / 239

页数：9

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