Can We Override Clopidogrel Resistance?

被引：119

作者：

Pena, Ana ^{[1
]}

Collet, Jean-Philippe ^{[1
]}

Hulot, Jean-Sebastien ^{[2
]}

Silvain, Johanne ^{[1
]}

Barthelemy, Olivier ^{[1
]}

Beygui, Farzin ^{[1
]}

Funck-Brentano, Christian ^{[2
]}

Montalescot, Gilles ^{[1
]}

机构：

[1] Univ Paris 06, INSERM 937, Inst Cardiol, Paris, France

[2] Hop La Pitie Salpetriere, AP HP, INSERM 956, Serv Pharmacol,Unite Pharmacogenet, F-75013 Paris, France

来源：

CIRCULATION | 2009年 / 119卷 / 21期

关键词：

ANTIPLATELET THERAPY; CORONARY;

D O I：

10.1161/CIRCULATIONAHA.108.857722

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2854 / 2857

页数：4

共 8 条

[1] Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease - Results of the Optimizing antiPlatelet Therapy In diabetes MellitUS (OPTIMUS) study [J].

Angiolillo, Dominick J. ;

Shoemaker, Steven B. ;

Desai, Bhaloo ;

Yuan, Hang ;

Charlton, Ronald K. ;

Bernardo, Esther ;

Zenni, Martin M. ;

Guzman, Luis A. ;

Bass, Theodore A. ;

Costa, Marco A. .

CIRCULATION, 2007, 115 (06) :708-716

[2]

Collet JP, 2008, CIRCULATION, V118, P1225, DOI [10.1161/CIRCULATIONAHA.108.776757, 10.1161/CIRCULATIONAHA.108.191108]

[3] Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study [J].

Collet, Jean-Philippe ;

Hulot, Jean-Sebastien ;

Pena, Anna ;

Villard, Eric ;

Esteve, Jean-Baptiste ;

Silvain, Johanne ;

Payot, Laurent ;

Brugier, Delphine ;

Cayla, Guillaume ;

Beygui, Farzin ;

Bensimon, Gilbert ;

Funck-Brentano, Christian ;

Montalescot, Gilles .

LANCET, 2009, 373 (9660) :309-317

[4] Cytochrorne P4502C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects [J].

Hulot, Jean-Sebastien ;

Bura, Alessandra ;

Villard, Eric ;

Azizi, Michel ;

Remones, Veronique ;

Goyenvalle, Catherine ;

Aiach, Martine ;

Lechat, Philippe ;

Gaussem, Pascale .

BLOOD, 2006, 108 (07) :2244-2247

[5] Drug-eluting stent and coronary thrombosis -: Biological mechanisms and clinical implications [J].

Luescher, Thomas F. ;

Steffel, Jan ;

Eberli, Franz R. ;

Joner, Michael ;

Nakazawa, Gaku ;

Tanner, Felix C. ;

Virmani, Renu .

CIRCULATION, 2007, 115 (08) :1051-1058

[6] Cardiovascular Death and Nonfatal Myocardial Infarction in Acute Coronary Syndrome Patients Receiving Coronary Stenting Are Predicted by Residual Platelet Reactivity to ADP Detected by a Point-of-Care Assay A 12-Month Follow-Up [J].

Marcucci, Rossella ;

Gori, Anna Maria ;

Paniccia, Rita ;

Giusti, Betti ;

Valente, Serafina ;

Giglioli, Cristina ;

Buonamici, Piergiovanni ;

Antoniucci, David ;

Abbate, Rosanna ;

Gensini, Gian Franco .

CIRCULATION, 2009, 119 (02) :237-242

[7] Cytochrome P-450 Polymorphisms and Response to Clopidogrel. [J].

Mega, Jessica L. ;

Close, Sandra L. ;

Wiviott, Stephen D. ;

Shen, Lei ;

Hockett, Richard D. ;

Brandt, John T. ;

Walker, Joseph R. ;

Antman, Elliott M. ;

Macias, William ;

Braunwald, Eugene ;

Sabatine, Marc S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (04) :354-362

[8] Genetic Determinants of Response to Clopidogrel and Cardiovascular Events. [J].

Simon, Tabassome ;

Verstuyft, Celine ;

Mary-Krause, Murielle ;

Quteineh, Lina ;

Drouet, Elodie ;

Meneveau, Nicolas ;

Steg, P. Gabriel ;

Ferrieres, Jean ;

Danchin, Nicolas ;

Becquemont, Laurent .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (04) :363-375

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