Sex-specific development of cortical monoamine levels in mouse

被引：24

作者：

Connell, S

Karikari, C

Hohmann, CF

机构：

[1] Morgan State Univ, Dept Biol, Baltimore, MD 21251 USA

[2] Morgan State Univ, Doctoral Studies Program Math & Sci Educ, Baltimore, MD 21251 USA

[3] NIAID, Parasit Dis Lab, NIH, Bethesda, MD 20892 USA

来源：

DEVELOPMENTAL BRAIN RESEARCH | 2004年 / 151卷 / 1-2期

关键词：

mouse; ontogeny; high performance liquid chromatography; dimorphism; mental health;

D O I：

10.1016/j.devbrainres.2004.03.008

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Several mental health disorders exhibit sex differences in monoamine levels associated with dimorphic cortical ontogeny. Studies in rodents support the notion that monoamines can profoundly modulate morphogenesis. Here, we show significant sex and hemisphere differences in BALB/cByJ mice on postnatal day 3 for dopamine (DA) and serotonin (5-TH), supporting the notion that sex differences in early monoaminergic ontogeny may result in dimorphic cortical development. Such sex differences may also influence differential behavioral and/or clinical outcomes. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：187 / 191

页数：5

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