Molecular events in skeletal muscle during disuse atrophy

被引:73
作者
Kandarian, SC [1 ]
Stevenson, EJ [1 ]
机构
[1] Boston Univ, Dept Hlth Sci, Boston, MA 02215 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2002年 / 30卷 / 03期
关键词
inactivity; disuse; cachexia; muscle wasting; proteolysis; calcium; ubiquitin; proteasome;
D O I
10.1097/00003677-200207000-00004
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
This review summarizes the current knowledge of the molecular processes underlying skeletal muscle atrophy due to disuse. Because the processes involved with muscle wasting due to illness are similar to disuse, this literature is used for comparison. Areas that are ripe for further study and that will advance our understanding of muscle atrophy are suggested.
引用
收藏
页码:111 / 116
页数:6
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