Severe heart valve calcification in a young patient with Werner syndrome

被引：9

作者：

Grubitzsch, H ^{[1
]}

Beholz, S ^{[1
]}

Wollert, HG ^{[1
]}

Eckel, L ^{[1
]}

机构：

[1] Klinikum Karlsburg, Clin Cardiothorac & Vasc Surg, Heart & Diabet Ctr Mecklenburg Vorpommern, D-17495 Karlsburg, Germany

来源：

CARDIOVASCULAR PATHOLOGY | 2000年 / 9卷 / 01期

关键词：

D O I：

10.1016/S1054-8807(99)00036-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Werner syndrome is a rare autosomal recessive disorder characterized by the appearance of premature aging. We report on severe aortic and mitral valve calcification in an 18-year-old girl, necessitating double valve replacement. These special cardiovascular findings are discussed with regard to diagnosis and treatment. Cardiovasc Pathol 2000,9:53-54 (C) 2000 by Elsevier Science Inc.

引用

页码：53 / 54

页数：2

共 6 条

[1] CARDIOVASCULAR FEATURES OF THE WERNER SYNDROME [J].

COHEN, JI ;

ARNETT, EN ;

KOLODNY, AL ;

ROBERTS, WC .

AMERICAN JOURNAL OF CARDIOLOGY, 1987, 59 (05) :493-495

[2] WERNERS SYNDROME - A REVIEW OF ITS SYMPTOMATOLOGY NATURAL HISTORY PATHOLOGIC FEATURES GENETICS AND RELATIONSHIP TO NATURAL AGING PROCESS [J].

EPSTEIN, CJ ;

MARTIN, GM ;

SCHULTZ, AL ;

MOTULSKY, AG .

MEDICINE, 1966, 45 (03) :177-+

[3] HOMOZYGOSITY MAPPING OF THE WERNER SYNDROME LOCUS (WRN) [J].

NAKURA, J ;

WIJSMAN, EM ;

MIKI, T ;

KAMINO, K ;

YU, CE ;

OSHIMA, J ;

FUKUCHI, K ;

WEBER, JL ;

PIUSSAN, C ;

MELARAGNO, MI ;

EPSTEIN, CJ ;

SCAPPATICCI, S ;

FRACCARO, M ;

FUJIWARA, Y ;

MATSUMURA, T ;

MURANO, S ;

YOSHIDA, S ;

SAIDA, T ;

OGIHARA, T ;

MARTIN, GM ;

SCHELLENBERG, GD .

GENOMICS, 1994, 23 (03) :600-608

[4]

Rolle F, 1997, ARCH MAL COEUR VAISS, V90, P1663

[5]

WERNER O, 1904, THESIS U KIEL KIEL

[6]

Yu CE, 1997, AM J HUM GENET, V60, P330

← 1 →