In situ self hardening bioactive composite for bone and dental surgery

被引：29

作者：

Turczyn, R

Weiss, P

Lapkowski, M

Daculsi, G

机构：

[1] Fac Chirurg Dent, INSERM 99 03, Equipe Rech Mat Interet Biol, UPRES EA 2159, F-44042 Nantes 01, France

[2] Silesian Tech Univ, Dept Chem, PL-44100 Gliwice, Poland

[3] Tech Univ Lodz, Dept Text Engn & Environm Sci, PL-43300 Bielsko Biala, Poland

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 2000年 / 11卷 / 02期

关键词：

biomaterial; hydroxyethylcellulose; silanised functional groups; hydrophilic gel;

D O I：

10.1163/156856200743661

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A new biomaterial is presented which consists of a cellulose derivative - silanised hydroxyethylcellulose (HEC-SIL) and biphasic calcium phosphate (BCP). Rheological properties of the polymer itself and its mixture with BCP are pH-dependent. At pH 10-12 HEC-SIL. is liquid and undergoes quick gellation at pH < 9. Similarly, the paste of HEC-SIL and BCP is fluid and injectable at higher pH and solidifies in biological solutions. The rate of this solidification can be easily controlled by the degree of substitution of hydroxyethylcellulose with silicoalkoxy groups.

引用

页码：217 / 223

页数：7

共 12 条

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