Influenza vaccination coverage among adult solid organ transplant recipients at three health maintenance organizations, 1995-2005

被引：36

作者：

Harris, KaLynne ^{[1
]}

Baggs, James ^{[1
]}

Davis, Robert L. ^{[1
]}

Black, Steven ^{[2
]}

Jackson, Lisa A. ^{[3
]}

Mullooly, John P. ^{[4
]}

Chapman, Louisa E. ^{[5
]}

机构：

[1] CDC, Immunizat Safety Off, Off Chief Sci Officer, Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[2] No Calif Kaiser Permanente, Vaccine Study Ctr, Pediat Vaccine Study Ctr, Oakland, CA 94612 USA

[3] Grp Hlth Ctr Hlth Studies, Seattle, WA 98101 USA

[4] Kaiser Permanente NW, Ctr Hlth Res, Portland, OR 97227 USA

[5] CDC, Off Director, Immunizat Serv Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA

来源：

VACCINE | 2009年 / 27卷 / 17期

关键词：

Allotransplantation; Influenza; Vaccine; ANTIBODY-RESPONSE; IMMUNE-RESPONSE; IMMUNIZATION; INFECTION; EFFICACY; CHILDREN; SAFETY; RECOMMENDATIONS; ASTHMA;

D O I：

10.1016/j.vaccine.2009.02.026

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Annual immunization against influenza is recommended for solid organ transplant (SOT) recipients. We used Vaccine Safety Datalink data from 1995 to 2005 to assess influenza vaccination during the first full vaccination season (September-February) following transplant among 1800 kidney, liver, and heart transplant recipients at three health maintenance organizations. Overall, 52% of recipients were vaccinated. Older age at transplant (age 50-64 years, OR 1.81, 95% CI 1.43-2.30; age >= 65 years, OR 1.94, 95% CI 1.39-2.69), receiving vaccination in the full season pre-transplant (OR 4.54, 95% Cl 3.67-5.60), and year of transplantation were significant predictors of post-transplant vaccination. Although vaccine coverage increased during study years, SOT recipients are under-immunized against influenza. Efforts to understand barriers to vaccination and increase education of physicians managing patients while awaiting and after receipt of transplant are needed. Published by Elsevier Ltd.

引用

页码：2335 / 2341

页数：7

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