Molecular characterization of multiresistant d-tartrate-positive Salmonella enterica serovar Paratyphi B isolates

被引：51

作者：

Miko, A ^{[1
]}

Guerra, B ^{[1
]}

Schroeter, A ^{[1
]}

Dorn, C ^{[1
]}

Helmuth, R ^{[1
]}

机构：

[1] Fed Inst Hlth Protect Consumers & Vet Med BgVV, Balt Salmonella Reference Lab, D-12277 Berlin, Germany

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 09期

关键词：

D O I：

10.1128/JCM.40.9.3184-3191.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Since 1996, the National Salmonella Reference Laboratory of Germany has received an increasing number of Salmonella enterica subsp. enterica serovar Paratyphi B isolates. Nearly all of these belonged to the dextrorotatory tartrate-positive variant (S. enterica subsp. enterica serovar Paratyphi B dT(+)), formerly called S. enterica subsp. enterica serovar Java. A total of 55 selected contemporary and older S. enterica subsp. enterica serovar Paratyphi B dT(+) isolates were analyzed by plasmid profiling, antimicrobial resistance testing, pulsed-field gel electrophoresis, IS200 profiling, and PCR-based detection of integrons. The results showed a high genetic heterogeneity among 10 old strains obtained from 1960 to 1993. In the following years, however, new distinct multiresistant S. enterica subsp. enterica serovar Paratyphi B dT(+) clones emerged, and one clonal lineage successfully displaced the older ones. Since 1994, 88% of the isolates investigated were multiple drug resistant. Today, a particular clone predominates in some German poultry production lines, poultry products, and various other sources. It was also detected in contemporary isolates from two neighboring countries as well.

引用

页码：3184 / 3191

页数：8

共 39 条

[1] COMPARATIVE-EVALUATION OF MOLECULAR TYPING OF STRAINS FROM A NATIONAL EPIDEMIC DUE TO SALMONELLA BRANDENBURG BY RIBOSOMAL-RNA GENE AND IS200 PROBES AND PULSED-FIELD GEL-ELECTROPHORESIS [J].