Polymorphism in molecular crystals: Stabilization of a metastable form by conformational mimicry

被引：299

作者：

Davey, RJ ^{[1
]}

Blagden, N ^{[1
]}

Potts, GD ^{[1
]}

Docherty, R ^{[1
]}

机构：

[1] ZENECA SPECIAL,RES DEPT,MANCHESTER M9 8ZS,LANCS,ENGLAND

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1997年 / 119卷 / 07期

关键词：

D O I：

10.1021/ja9626345

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A combined modeling and experimental strategy has been applied to the problem of stabilisation of a metastable conformational polymorph. For the first time additives have been successfully selected which by virtue of their conformation are able to selectively inhibit the appearance of the stable beta polymorph of L-glutamic acid and hence stabilize the metastable alpha structure.

引用

页码：1767 / 1772

页数：6

共 26 条

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