Viral-encoded cyclins

被引：26

作者：

Laman, H

Mann, DJ

Jones, NC

机构：

[1] Imperial Canc Res Fund, Oncol Mol Lab, London WC2A 3PX, England

[2] Brunel Univ, Dept Biol Sci, Uxbridge UB3 3PH, Middx, England

[3] Christie Hosp NHS Trust, Paterson Inst Canc Res, Manchester M20 4BX, Lancs, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2000年 / 10卷 / 01期

关键词：

D O I：

10.1016/S0959-437X(99)00045-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

D-type cyclin homologs have been found in the genomes of herpesviruses associated with neoplasias. They appear to exploit features of G(1) cyclins but extend their properties to allow for deregulation of the cell cycle. Advances in the study of the molecular basis for these novel features as well as the potential role of viral cyclins in tumorigenesis are addressed.

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收藏

页码：70 / 74

页数：5

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