Homologous recombination: Down to the wire

被引:30
作者
Wyman, C
Kanaar, R
机构
[1] Erasmus MC, Dept Cell Biol & Genet, NL-3000 DR Rotterdam, Netherlands
[2] Erasmus MC, Dept Radiat Oncol, NL-3000 DR Rotterdam, Netherlands
关键词
D O I
10.1016/j.cub.2004.07.049
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Exchange of strands between homologous DNA molecules is catalyzed by evolutionarily conserved recombinases. These proteins can occur in different quaternary arrangements: rings or helical filaments. Recent results reveal that recombinase function follows from the filamentous form.
引用
收藏
页码:R629 / R631
页数:3
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