Screening Brazilian plant species for in vitro inhibition of 5-lipoxygenase

被引：24

作者：

Braga, FC

Wagner, H

Lombardi, JA

de Oliveira, AB

机构：

[1] Univ Fed Minas Gerais, Fac Farm, BR-30180112 Belo Horizonte, MG, Brazil

[2] Univ Munich, Inst Pharm, Zentrum Pharmaforsch Pharmazeut Biol, Munich, Germany

[3] Univ Fed Minas Gerais, ICB, Dept Bot, BR-30180112 Belo Horizonte, MG, Brazil

来源：

PHYTOMEDICINE | 2000年 / 6卷 / 06期

关键词：

Hedychium coronarium; Hymenaea courbaril; Xylopia frutessens; 5-lipoxygenase inhibition;

D O I：

10.1016/S0944-7113(00)80073-2

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Plants from the Brazilian flora were evaluated for the inhibition of 5-lipoxygenase. The species were selected based on their traditional use and on a chemosystematic approach. In total, 19 species belonging to 13 families have been investigated. Hedychium coronarium J. Koenig (Zingiberaceae), Xylopia frutescens Aubl. (Annonaceae) and Hymenaea courbaril L. (Leguminosae) presented a high 5-lipoxygenase inhibitory activity. Some hypothesis about the nature of the active compounds are discussed, based on reports of the chemical constitution of these species or other species from the same botanical family.

引用

页码：447 / 452

页数：6

共 36 条

[1] ETHNOBOTANY OF HILL TRIBES OF NORTHERN THAILAND .2. LAHU MEDICINAL-PLANTS [J].