Doxorubicin in sterically stabilized liposomes

被引：261

作者：

Lasic, DD

机构：

[1] Newark, CA 94560

来源：

NATURE | 1996年 / 380卷 / 6574期

关键词：

D O I：

10.1038/380561a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Improved liposome stability and drug retention significantly increase the anticancer activity of encapsulated doxorubicin (Doxil), enhancing the effectiveness of chemotherapy and potentially reducing its toxicity.

引用

页码：561 / 562

页数：2

共 28 条

[1] SURROGATE CELLS OR TROJAN HORSES - THE DISCOVERY OF LIPOSOMES
BANGHAM, AD
[J]. BIOESSAYS, 1995, 17 (12) : 1081 - 1088
[2] LIPOSOMES FOR THE SUSTAINED DRUG RELEASE INVIVO
BLUME, G
CEVC, G
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1029 (01) : 91 - 97
[3] A RIGOROUS THEORY OF REMOTE LOADING OF DRUGS INTO LIPOSOMES
CEH, B
LASIC, DD
[J]. LANGMUIR, 1995, 11 (09) : 3356 - 3368
[4] LIPOSOMAL DOXORUBICIN-INDUCED TOXICITY - DEPLETION AND IMPAIRMENT OF PHAGOCYTIC-ACTIVITY OF LIVER MACROPHAGES
DAEMEN, T
HOFSTEDE, G
KATE, MTT
BAKKERWOUDENBERG, IAJM
SCHERPHOF, GL
[J]. INTERNATIONAL JOURNAL OF CANCER, 1995, 61 (05) : 716 - 721
[5] POLYMERS AT AN INTERFACE - A SIMPLIFIED VIEW
DEGENNES, PG
[J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 1987, 27 (3-4) : 189 - 209
[6] GABIZON A, 1994, CANCER RES, V54, P987
[7] CLINICAL-STUDIES OF LIPOSOME-ENCAPSULATED DOXORUBICIN
GABIZON, A
ISACSON, R
LIBSON, E
KAUFMAN, B
UZIELY, B
CATANE, R
BENDOR, CG
RABELLO, E
CASS, Y
PERETZ, T
SULKES, A
CHISIN, R
BARENHOLZ, Y
[J]. ACTA ONCOLOGICA, 1994, 33 (07) : 779 - 786
[8] THE PHOSPHOLIPID COMPONENT OF SMALL UNILAMELLAR LIPOSOMES CONTROLS THE RATE OF CLEARANCE OF ENTRAPPED SOLUTES FROM THE CIRCULATION
GREGORIADIS, G
SENIOR, J
[J]. FEBS LETTERS, 1980, 119 (01) : 43 - 46
[9] TRANSMEMBRANE AMMONIUM-SULFATE GRADIENTS IN LIPOSOMES PRODUCE EFFICIENT AND STABLE ENTRAPMENT OF AMPHIPATHIC WEAK BASES
HARAN, G
COHEN, R
BAR, LK
BARENHOLZ, Y
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1151 (02) : 201 - 215
[10] ISRAELACHVILI JN, 1985, SURFACE INTERPARTICL

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