Intracytoplasmic sperm injection: Results from Norfolk, USA

The results of 92 consecutive couples who underwent 102 cycles of in-vitro fertilization (IVF) augmented with intracytoplasmic sperm injection (ICSI) were analysed, Inclusion criteria were previous total failed fertilization or unsuitable sperm parameters for conventional IVF, The rate of diploid fertilization was 60.9%; the implantation rate per embryo was 12.1%, and the ongoing pregnancy rate per transfer was 26.8%, None of the sperm parameters of the original or processed semen sample were correlated with ICSI outcome, Conversely, female age and basal serum concentrations of follicle stimulating hormone (FSH) had a significant impact on implantation and pregnancy rates, ICSI has become a very successful therapy in overcoming different types of male infertility.