Acute effects of caffeine on heart rate variability

被引：70

作者：

Sondermeijer, HP

van Marle, AGJ

Kamen, P

Krum, H ^{[1
]}

机构：

[1] Monash Univ, Alfred Hosp, Clin Pharmacol Unit, Dept Epidemiol & Prevent Med, Prahran, Vic 3181, Australia

[2] Monash Univ, Alfred Hosp, Dept Med, Prahran, Vic 3181, Australia

[3] Leiden Univ, Leiden, Netherlands

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2002年 / 90卷 / 08期

关键词：

D O I：

10.1016/S0002-9149(02)02725-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute caffeine ingestion has been found to increase blood pressure and sympathetic activity in nonhabitual coffee drinkers; however, the effects. of caffeine on parasympathetic nervous system activity have seldom been explored. After acute ingestion of caffeine in 10 normal subjects, we found blood pressures to be significantly increased, and measures of parasympathetic nervous system activity significantly decreased compared with measures after placebo ingestion.

引用

页码：906 / +

页数：3

共 10 条

[1] Evaluation of electrocardiographic and hemodynamic effects of caffeine with acute dosing in healthy volunteers [J].

Ammar, R ;

Song, JC ;

Kluger, J ;

White, CM .

PHARMACOTHERAPY, 2001, 21 (04) :437-442

[2]

Corti R, 2000, EUR HEART J, V21, P105

[3] Autonomic tone as a cardiovascular risk factor: The dangers of chronic fight or flight [J].

Curtis, BM ;

O'Keeffe, JH .

MAYO CLINIC PROCEEDINGS, 2002, 77 (01) :45-54

[4] The revival of heart rate [J].

Ferrari, R ;

Rapezzi, C ;

Lombardi, F .

EUROPEAN HEART JOURNAL, 1999, 20 (12) :853-854

[5] COFFEE, CAFFEINE, AND CARDIOVASCULAR-DISEASE IN MEN [J].

GROBBEE, DE ;

RIMM, EB ;

GIOVANNUCCI, E ;

COLDITZ, G ;

STAMPFER, M ;

WILLETT, W .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (15) :1026-1032

[6] Caffeine enhances modulation of parasympathetic nerve activity in humans: Quantification using power spectral analysis [J].

Hibino, G ;

Moritani, T ;

Kawada, T ;

Fushiki, T .

JOURNAL OF NUTRITION, 1997, 127 (07) :1422-1427

[7] Poincare plot of heart rate variability allows quantitative display of parasympathetic nervous activity in humans [J].

Kamen, PW ;

Krum, H ;

Tonkin, AM .

CLINICAL SCIENCE, 1996, 91 (02) :201-208

[8]

KAWACHI I, 1994, BRIT HEART J, V72, P269

[9] Acute effect of caffeine on arterial stiffness and aortic pressure waveform [J].

Mahmud, A ;

Feely, J .

HYPERTENSION, 2001, 38 (02) :227-231

[10] Pressure-altering agents affect central aortic pressures more than is apparent from upper limb measurements in hypertensive patients - The role of arterial wave reflections [J].

Vlachopoulos, C ;

Hirata, K ;

O'Rourke, MF .

HYPERTENSION, 2001, 38 (06) :1456-1460

← 1 →