Insights into the general and efficient cross McMurry reactions between ketones

被引：139

作者：

Duan, Xin-Fang ^{[1
]}

Zeng, Jing ^{[1
]}

Lu, Jia-Wei ^{[1
]}

Zhang, Zhan-Bin ^{[1
]}

机构：

[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 26期

关键词：

D O I：

10.1021/jo061644d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The selective cross McMurry couplings of diaryl or aryl ketones with various substituted ketones were achieved in 53-94% isolated yields. It is believed that the strong affinity of the substituents to the low-valent titanium surface plays an important role in regards to moderating selectivity. Through the introduction of such substituents followed by their removal post McMurry coupling, structurally similar ketones can be effectively cross-coupled.

引用

页码：9873 / 9876

页数：4

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