Overview of stem cells and imaging modalities for cardiovascular diseases

被引：32

作者：

Chang, Gwendolen Y.

Xie, Xiaoyan

Wu, Joseph C.

机构：

[1] Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA

[2] Stanford Univ, Sch Med, Dept Radiol, Mol Imaging Program, Stanford, CA 94305 USA

来源：

JOURNAL OF NUCLEAR CARDIOLOGY | 2006年 / 13卷 / 04期

关键词：

D O I：

10.1016/j.nuclcard.2006.05.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Stem cell therapy is emerging as a promising approach to treat heart diseases. Considerable evidence from experimental studies and initial clinical trials suggests that stem cell transplantation promotes systolic function and prevent ventricular remodeling. However, the specific mechanisms by which stem cells improve heart function remain largely unknown. In addition, interpreting the long-term effects of stem cell therapy is difficult because of the limitations of conventional techniques. The recent development of molecular imaging techniques offers great potential to address these critical issues by noninvasively tracking the fate of the transplanted cells. This review offers a focused discussion on the use of stem cell therapy and imaging in the context of cardiology.

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收藏

页码：554 / 569

页数：16

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