Signaling downstream of p38 in psoriasis

被引：19

作者：

Arthur, J. Simon C. ^{[1
]}

Darragh, Joanne ^{[1
]}

机构：

[1] Univ Dundee, Sch Life Sci, MRC, Prot Phosphorylat Unit, Dundee DD1 5EH, Scotland

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2006年 / 126卷 / 08期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1038/sj.jid.5700280

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Psoriasis is an inflammatory skin disease characterized by infiltration of the skin by T cells and increased production of pro-inflammatory cytokines. Two recent reports show that the p38-Activated kinases mitogen-activated protein kinaseactivated protein kinase 2 and mitogen- and stress- activated protein kinase are activated in psoriatic skin and may contribute to the production of proinflammatory cytokines.

引用

页码：1689 / 1691

页数：4

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