Metabolic aspects of sleep apnea

被引：43

作者：

Grunstein, RR

机构：

来源：

SLEEP | 1996年 / 19卷 / 10期

关键词：

sleep apnea; obesity; energy expenditure; growth hormone; insulin; serotonin;

D O I：

10.1093/sleep/19.suppl_10.S218

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Sleep apnea is associated with abnormalities in metabolic function. First, there is a strong epidemiological link between central obesity and sleep apnea. Some evidence suggests that sleep apnea may promote weight gain or prevent weight loss by several mechanisms: reduction in anabolic (growth hormone and testosterone) hormone secretion, influences on energy balance and insulin sensitivity, and altered central serotonergic tone.

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页码：S218 / S220

页数：3

相关论文

共 14 条

[1] TREATMENT OF ADULTS WITH GROWTH-HORMONE (GH) DEFICIENCY WITH RECOMBINANT HUMAN GH [J].

BENGTSSON, BA ;

EDEN, S ;

LONN, L ;

KVIST, H ;

STOKLAND, A ;

LINDSTEDT, G ;

BOSAEUS, I ;

TOLLI, J ;

SJOSTROM, L ;

ISAKSSON, OGP .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1993, 76 (02) :309-317

[2] METABOLISM DURING NORMAL, FRAGMENTED, AND RECOVERY SLEEP [J].

BONNET, MH ;

BERRY, RB ;

ARAND, DL .

JOURNAL OF APPLIED PHYSIOLOGY, 1991, 71 (03) :1112-1118

[3] OBSTRUCTIVE SLEEP-APNEA IN OBESE NONINSULIN-DEPENDENT DIABETIC-PATIENTS - EFFECT OF CONTINUOUS POSITIVE AIRWAY PRESSURE TREATMENT ON INSULIN RESPONSIVENESS [J].

BROOKS, B ;

CISTULLI, PA ;

BORKMAN, M ;

ROSS, G ;

MCGHEE, S ;

GRUNSTEIN, RR ;

SULLIVAN, CE ;

YUE, DK .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1994, 79 (06) :1681-1685

[4] EFFECT OF TESTOSTERONE ADMINISTRATION ON UPPER AIRWAY COLLAPSIBILITY DURING SLEEP [J].

CISTULLI, PA ;

GRUNSTEIN, RR ;

SULLIVAN, CE .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1994, 149 (02) :530-532

[5]

GRUNSTEIN R, 1993, INT J OBESITY, V17, P533

[6] IMPACT OF SELF-REPORTED SLEEP-BREATHING DISTURBANCES ON PSYCHOSOCIAL PERFORMANCE IN THE SWEDISH OBESE SUBJECTS (SOS) STUDY [J].

GRUNSTEIN, RR ;

STENLOF, K ;

HEDNER, JA ;

SJOSTROM, L .

SLEEP, 1995, 18 (08) :635-643

[7] NEURO-ENDOCRINE DYSFUNCTION IN SLEEP-APNEA - REVERSAL BY CONTINUOUS POSITIVE AIRWAYS PRESSURE THERAPY [J].

GRUNSTEIN, RR ;

HANDELSMAN, DJ ;

LAWRENCE, SJ ;

BLACKWELL, C ;

CATERSON, ID ;

SULLIVAN, CE .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1989, 68 (02) :352-358

[8]

GRUNSTEIN RR, 1993, AM REV RESPIR DIS, V147, pA686

[9]

GRUNSTEIN RR, 1995, INT J OBESITY, V19, P410

[10]

GUNSTEIN RR, 1993, SLEEP BREATHING