Pathophysiology of prediabetes

被引：110

作者：

Abdul-Ghani, Muhammad A. ^{[1
]}

DeFronzo, Ralph A. ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Diabet Div, San Antonio, TX 78229 USA

来源：

CURRENT DIABETES REPORTS | 2009年 / 9卷 / 03期

关键词：

IMPAIRED GLUCOSE-TOLERANCE; AMERICAN-DIABETES-ASSOCIATION; BETA-CELL DYSFUNCTION; FREE FATTY-ACID; INSULIN-RESISTANCE; FASTING GLUCOSE; CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME; PLASMA-GLUCOSE; CRITERIA;

D O I：

10.1007/s11892-009-0032-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The term prediabetes refers to subjects with impaired fasting glucose and/or impaired glucose tolerance who are at increased risk for type 2 diabetes mellitus. Although both types of patients are at increased risk for developing type 2 diabetes mellitus and cardiovascular disease, they manifest distinct metabolic abnormalities. In this article, we summarize the metabolic abnormalities that characterize each state and the contribution of these metabolic abnormalities to the increased risk of diabetes and cardiovascular disease.

引用

页码：193 / 199

页数：7

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