Genome-wide identification of CRISPR/Cas9 off-targets in human genome

被引:102
作者
Duan, Jinzhi [1 ,2 ,3 ]
Lu, Guangqing [1 ,2 ,3 ]
Xie, Zhan [3 ]
Lou, Mingliang [3 ]
Luo, Jiao [3 ]
Guo, Lei [3 ]
Zhang, Yu [1 ,2 ,3 ]
机构
[1] Peking Union Med Coll, Grad Program, Beijing 100730, Peoples R China
[2] Chinese Acad Med Sci, Beijing 100730, Peoples R China
[3] Natl Inst Biol Sci, Beijing 102206, Peoples R China
关键词
HUMAN-CELLS; RNA; DNA; CAS9; NUCLEASES; SPECIFICITY;
D O I
10.1038/cr.2014.87
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:1009 / 1012
页数:4
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