A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals

被引：90

作者：

Herrera-perez, Diana ^{[1
]}

Haslam, Alyson ^{[1
]}

Crain, Tyler ^{[1
]}

Gill, Jennifer ^{[1
]}

Livingston, Catherine ^{[2
]}

Kaestner, Victoria ^{[1
]}

Hayes, Michael ^{[3
]}

Morgan, Dan ^{[4
]}

Cifu, Adam S. ^{[5
]}

Prasad, Vinay ^{[6
,7
]}

机构：

[1] Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR 97201 USA

[2] Oregon Hlth & Sci Univ, Sch Med, Portland, OR 97201 USA

[3] Oregon Hlth & Sci Univ, Div Internal Med, Portland, OR 97201 USA

[4] Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA

[5] Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA

[6] Oregon Hlth & Sci Univ, Knight Canc Inst, Dept Publ Hlth & Prevent Med, Ctr Hlth Care Eth, Portland, OR 97201 USA

[7] Oregon Hlth & Sci Univ, Dept Med, Portland, OR 97201 USA

来源：

ELIFE | 2019年 / 8卷

关键词：

EXTERNAL HIP PROTECTORS; OFF-PUMP; ON-PUMP; CARE; MANAGEMENT; METAANALYSIS; MORTALITY; INSOMNIA; THERAPY; SURGERY;

D O I：

10.7554/eLife.45183

中图分类号：

Q [生物科学];

学科分类号：

090105 [作物生产系统与生态工程];

摘要：

The ability to identify medical reversals and other low-value medical practices is an essential prerequisite for efforts to reduce spending on such practices. Through an analysis of more than 3000 randomized controlled trials (RCTs) published in three leading medical journals (the Journal of the American Medical Association, the Lancet, and the New England Journal of Medicine), we have identified 396 medical reversals. Most of the studies (92%) were conducted on populations in high-income counties, cardiovascular disease was the most common medical category (20%), and medication was the most common type of intervention (33%).

引用

页数：19

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