Polymorphism in the CYP2D6 tamoxifen-metabolizing gene influences clinical effect but not hot flashes:: Data from the Italian tamoxifen trial

被引:99
作者
Bonanni, Bernardo [1 ]
Macis, Debora
Maisonneuve, Patrick
Johansson, Harriet A.
Gucciardo, Giacomo
Oliviero, Pasquale
Travaglini, Roberto
Muraca, Maria G.
Rotmensz, Nicole
Veronesi, Umberto
Decensi, Andrea U.
机构
[1] European Inst Oncol, Milan, Italy
[2] Osped San Camillo Forlanini, Rome, Italy
[3] Fdn Pascale, Naples, Italy
[4] Fdn Maugeri, Pavia, Italy
[5] Ctr Studio & Prevenz Oncol, I-50131 Florence, Italy
[6] Ente Osped Osped Galliera, Genoa, Italy
关键词
D O I
10.1200/JCO.2006.06.8072
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:3708 / 3709
页数:2
相关论文
共 1 条
[1]   Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes [J].
Goetz, MP ;
Rae, JM ;
Suman, VJ ;
Safgren, SL ;
Ames, MM ;
Visscher, DW ;
Reynolds, C ;
Couch, FJ ;
Lingle, WL ;
Flockhart, DA ;
Desta, Z ;
Perez, EA ;
Ingle, JN .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (36) :9312-9318