Resistant Candida parapsilosis associated with long term fluconazole prophylaxis in an animal model

被引：26

作者：

Yoder, BA ^{[1
]}

Sutton, DA

Winter, V

Coalson, JJ

机构：

[1] Univ Texas, Hlth Sci Ctr, Dept Med & Physiol, SW Fdn Biomed Res, San Antonio, TX 78285 USA

[2] Univ Texas, Hlth Sci Ctr, Dept Pathol, San Antonio, TX 78285 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2004年 / 23卷 / 07期

关键词：

fluconazole; Candida; resistance; neonate; baboon;

D O I：

10.1097/01.inf.0000128777.22022.47

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report an increased occurrence of fluconazole-resistant Candida parapsilosis after a 4-year period of antifungal prophylaxis in a premature animal neonatal intensive care unit. Although prevention of nosocomial fungal infections in premature infants is desirable, implementation of fluconazole prophylaxis should be undertaken with caution. Where such programs are in place, evaluation of fungal isolates for drug resistance should be considered.

引用

页码：687 / 688

页数：2

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