Improving the assessment of outcomes in stroke - Use of a structured interview to assign grades on the modified Rankin Scale

被引:593
作者
Wilson, JTL [1 ]
Hareendran, A
Grant, M
Baird, T
Schulz, UGR
Muir, KW
Bone, I
机构
[1] Univ Stirling, Dept Psychol, Stirling FK9 4LA, Scotland
[2] Pfizer Ltd, Outcomes Res, Sandwich CT13 9NJ, Kent, England
[3] Inst Neurol Sci, Dept Neurol, Glasgow, Lanark, Scotland
关键词
clinical trials; disability evaluation; outcome; outcome assessment;
D O I
10.1161/01.STR.0000027437.22450.BD
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and Purpose-The modified Rankin Scale is widely used to assess changes in activity and lifestyle after stroke but it has been criticized for its subjectivity The purpose of the present study was to compare conventional assessment on the modified Rankin Scale with assessment through a structured interview Methods-Sixty three patients with stroke 6 to 24 months previously were interviewed and graded independently on the modified Rankin Scale by 2 observers These observers then underwent training in use of a structured interview for the scale that covered 5 areas of everyday function Eight weeks after the first assessment the same observers reassessed 58 of these patients using the structured interview Results-Interrater reliability was measured with the kappa statistic (weighted with quadratic weights) For the scale applied conventionally overall agreement between the 2 raters was 57% (kappa(w)=0 78) 1 rater assigned significantly lower grades than the other (P=0 048) On the structured interview the overall agreement between raters was 78% (kappa(w)=0 93) and there was no overall difference between raters in grades assigned (P=0 17) Rankin grades from the conventional assessment and the structured interview were highly correlated but there was significantly less disagreement between raters when the structured interview was used (P=0 004) Conclusions-Variability and bias between raters in assigning patients to Rankin grades may be reduced by use of a structured interview Use of a structured interview for the scale could potentially improve the quality of results from clinical studies in stroke.
引用
收藏
页码:2243 / 2246
页数:4
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