Death associated with rifampin and pyrazinamide 2-month treatment of latent mycobacterium tuberculosis

被引：10

作者：

Medinger, A ^{[1
]}

机构：

[1] Dept Vet Affairs Med Ctr, Washington, DC USA

来源：

CHEST | 2002年 / 121卷 / 05期

关键词：

drug toxicity; latent tuberculosis treatment; Mycobacterium tuberculosis; pyrazinamide; rifampin;

D O I：

10.1378/chest.121.5.1710

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

We present the case of an elderly patient who died of fulminant hepatic failure in the course of receiving 2 months of treatment with pyrazinamide and rifampin for his latent tuberculosis. This 2-month course of treatment for latent tuberculosis is one of four options recently recommended by the Centers for Disease Control and Prevention. We discuss the safety of using this two-drug regimen to treat latent tuberculosis in stable elderly patients.

引用

页码：1710 / 1712

页数：3

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