Synthesis of aryl azides via post-cleavage modification of polymer-bound triazenes

被引:31
作者
Avemaria, F
Zimmermann, V
Bräse, S
机构
[1] Univ Bonn, Kekule Inst Organ Chem & Biochem, D-53121 Bonn, Germany
[2] Univ Karlsruhe, Inst Organ Chem, D-76131 Karlsruhe, Germany
关键词
aryl azides; post-cleavage modification; polymer-bound triazenes;
D O I
10.1055/s-2004-52298
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Starting from immobilized arenes on the triazene T1 linker resin, cleavage was achieved by trifluoroacetic acid in the presence of trimethylsilyl azide to obtain aryl azides in good yields and excellent purities. A novel cleavage protocol has been introduced and analytical and preparative applications have been presented.
引用
收藏
页码:1163 / 1166
页数:4
相关论文
共 65 条
  • [1] Annis D. A., 1998, ANGEW CHEM, V110, P2010
  • [2] Annis DA, 1998, ANGEW CHEM INT EDIT, V37, P1907, DOI 10.1002/(SICI)1521-3773(19980803)37:13/14<1907::AID-ANIE1907>3.0.CO
  • [3] 2-A
  • [4] Bräse S, 2000, CHIM OGGI, V18, P14
  • [5] Solid-phase synthesis of substituted cinnolines by a Richter type cleavage protocol
    Bräse, S
    Dahmen, S
    Heuts, J
    [J]. TETRAHEDRON LETTERS, 1999, 40 (34) : 6201 - 6203
  • [6] Bräse S, 2000, CHEM-EUR J, V6, P1899, DOI 10.1002/1521-3765(20000602)6:11<1899::AID-CHEM1899>3.0.CO
  • [7] 2-M
  • [8] Bräse S, 1998, ANGEW CHEM INT EDIT, V37, P3413, DOI 10.1002/(SICI)1521-3773(19981231)37:24<3413::AID-ANIE3413>3.0.CO
  • [9] 2-K
  • [10] Bräse S, 1999, ANGEW CHEM INT EDIT, V38, P1071, DOI 10.1002/(SICI)1521-3773(19990419)38:8<1071::AID-ANIE1071>3.0.CO