Cytotoxicity study of some Ti alloys used as biomaterial

被引：66

作者：

Donato, Tatiani A. G. ^{[1
]}

de Almeida, Luciano H. ^{[1
]}

Nogueira, Renata A. ^{[1
]}

Niemeyer, Terlize C. ^{[1
]}

Grandini, Carlos R. ^{[1
]}

Caram, Rubens ^{[2
]}

Schneider, Sandra G. ^{[3
]}

Santos, Arnaldo R., Jr. ^{[4
]}

机构：

[1] UNESP, Grp Relaxacoes Anelast, BR-17033360 Bauru, SP, Brazil

[2] Univ Estadual Campinas, Dept Mat Engn, BR-13083970 Campinas, SP, Brazil

[3] USP, Escola Engn Lorena, BR-12600970 Lorena, SP, Brazil

[4] Univ Fed Abc, Ctr Ciencias Nat & Humanas, BR-09090400 Santo Andre, SP, Brazil

来源：

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2009年 / 29卷 / 04期

基金：

巴西圣保罗研究基金会;

关键词：

Biocompatibility; Ti alloys; Cytotoxicity; Cell culture; TITANIUM-ALLOYS; VERO CELLS; MECHANICAL-PROPERTIES; PLASMA IMMERSION; BEHAVIOR; IRRADIATION; COMPOSITES; WEAR;

D O I：

10.1016/j.msec.2008.10.021

中图分类号：

T [工业技术];

学科分类号：

120111 [工业工程];

摘要：

An implanted material is considered biocompatible, if adverse and uncontrollable reactions don't exist in the biological system. in this sense, biocompatibility tests made in the constituent materials are very important so that the implants have Success. The in vitro cytotoxicity tests represent the initial phase of the process, and Could be considered as a pre-selection of those materials. in vitro techniques using cell culture have become widely used in the evaluation of biomaterial cytotoxicity, which has contributed to their standardization and the substitution of in vivo tests. This paper shows a study of the in vitro cytotoxicity of two Ti based alloys, Ti-13Nb-13Zr and Ti-35Nb-7Zr-5Ta, in the as-received condition and after heat treated. The results show that the alloys presented no cytotoxic effects in the studied conditions. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：1365 / 1369

页数：5

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