A three-step and enantioselective synthesis of (-)-(S)- or (+)-(R)-2-(furan-3-yl)-3,6-dihydro-2H-pyrans

被引：13

作者：

de Rosa, M ^{[1
]}

Solladié-Cavallo, A

Scettri, A

机构：

[1] Univ Salerno, Dipartimento Chim, I-84081 Baronissi, SA, Italy

[2] Univ Strasbourg, ECPM, F-67087 Strasbourg 2, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 10期

关键词：

furyl-dihydropyranes; asymmetric allylation; ring-closing metathesis;

D O I：

10.1016/S0040-4039(99)02337-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantiomerically enriched (3-furyl)-2-pyran derivatives, key-intermediates in the synthesis of the pharmacophoric pyranofuranone system of the bioactive natural products manoalide and cacospongionolide B, are easily accessible by a rapid sequence involving a chiral allylation and a ring closing metathesis reaction. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

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页码：1593 / 1596

页数：4

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