Synaptogenic Proteins and Synaptic Organizers: "Many Hands Make Light Work"

被引:29
作者
Brose, Nils [1 ]
机构
[1] Max Planck Inst Expt Med, Dept Mol Neurobiol, D-37075 Gottingen, Germany
关键词
NEUROLIGINS; HANDEDNESS; MOLECULES;
D O I
10.1016/j.neuron.2009.02.014
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Synaptogenesis is thought to be mediated by cell adhesion proteins, which induce the initial contact between an axon and its target cell and subsequently recruit and organize the presynaptic and postsynaptic protein machinery required for synaptic transmission. A new study by Linhoff and colleagues in this issue of Neuron identifies adhesion proteins of the LRRTM family as novel synaptic organizers.
引用
收藏
页码:650 / 652
页数:3
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