The interface between cell and developmental biology

被引:3
作者
Tahinci, E [1 ]
Lee, E [1 ]
机构
[1] Vanderbilt Univ, Sch Med, Dept Cell & Dev Biol, MCN Learned Labs, Nashville, TN 37232 USA
关键词
D O I
10.1016/j.gde.2004.06.013
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Cell differentiation, morphology, migration, polarity, intercellular communication and adhesion are all cellular processes that control embryo morphogenesis and lie at the interface of cell and developmental biology. The interface between these two fields is best illustrated, however, in studies of axiation and cytoskeletal remodeling during development. Recent advances reveal novel mechanisms for axiation, including the role of RNA and protein degradation in regulating the timely expression of morphogenetic signals. Significant progress has also been made in identifying components of the cytoskeleton and the extracellular matrix that mediate embryonic cell migration and polarity. Cellular processes at the interface of cell and developmental biology are overseen by the Writ signaling cascade that coordinates both axiation and cytoskeletal remodeling during development.
引用
收藏
页码:361 / 366
页数:6
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