Decrease of serum dipeptidylpeptidase activity in severe sepsis patients: relationship to procalcitonin

被引：17

作者：

Bergmann, A

Bohuon, C

机构：

[1] UER Pharm, Lab Immunotoxicol, F-92296 Chatenay Malabry, France

[2] Brahms Diagnost, D-12099 Berlin, Germany

来源：

CLINICA CHIMICA ACTA | 2002年 / 321卷 / 1-2期

关键词：

serum dipeptidylpeptidase; DPP IV; severe sepsis; procalcitonin; immunomodulation;

D O I：

10.1016/S0009-8981(02)00042-6

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 [基础医学];

摘要：

A significant decrease of DPP IV activity has been found in patients with severe sepsis in relationship to the increase of procalcitonin. These findings might be explained by the high concentration of other substrates for DPP IV present in these patients. It can be hypothesized that this enzymatic decrease is bound to some changes in immunomodulation. Further studies will be necessary to elucidate the clinical importance of these findings. (C) 2002 Published by Elsevier Science B.V.

引用

页码：123 / 126

页数：4

共 16 条

[1]

HIGH SERUM PROCALCITONIN CONCENTRATIONS IN PATIENTS WITH SEPSIS AND INFECTION [J].