Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri

被引:239
作者
Allison, GE [1 ]
Verma, NK [1 ]
机构
[1] Australian Natl Univ, Fac Sci, Div Biochem & Mol Biol, Canberra, ACT 0200, Australia
基金
英国医学研究理事会;
关键词
D O I
10.1016/S0966-842X(99)01646-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
O-antigen modification (serotype conversion) in Shigella flexneri, which is an important virulence determinant, is conferred by temperate bacteriophages. Several serotype-converting phages have been isolated and preliminary characterization has identified the genes involved in O-antigen modification, and has also provided insight into the molecular biology of these phages.
引用
收藏
页码:17 / 23
页数:7
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