A novel approach to cancer staging: application to esophageal cancer

被引:56
作者
Ishwaran, Hemant [1 ]
Blackstone, Eugene H. [2 ]
Apperson-Hansen, Carolyn [1 ]
Rice, Thomas W. [2 ]
机构
[1] Cleveland Clin, Dept Quantitat Hlth Sci, Cleveland, OH 44195 USA
[2] Cleveland Clin, Dept Thorac & Cardiovasc Surg, Cleveland, OH 44195 USA
关键词
Predicted survival; Random forests; Survival curves; TNM; AMERICAN JOINT COMMITTEE; CLASSIFICATION; CARCINOMA; REGRESSION; SELECTION;
D O I
10.1093/biostatistics/kxp016
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A novel 3-step random forests methodology involving survival data (survival forests), ordinal data (multiclass forests), and continuous data (regression forests) is introduced for cancer staging. The methodology is illustrated for esophageal cancer using worldwide esophageal cancer collaboration data involving 4627 patients.
引用
收藏
页码:603 / 620
页数:18
相关论文
共 28 条
[1]  
[Anonymous], 2002, AJCC CANC STAG MAN
[2]  
[Anonymous], AJCC CANC STAG MAN
[3]   Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma [J].
Balch, CM ;
Buzaid, AC ;
Soong, SJ ;
Atkins, MB ;
Cascinelli, N ;
Coit, DG ;
Fleming, ID ;
Gershenwald, JE ;
Houghton, A ;
Kirkwood, JM ;
McMasters, KM ;
Mihm, MF ;
Morton, DL ;
Reintgen, DS ;
Ross, MI ;
Sober, A ;
Thompson, JA ;
Thompson, JF .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (16) :3635-3648
[4]  
Breiman L, 1996, ANN STAT, V24, P2350
[5]   Random forests [J].
Breiman, L .
MACHINE LEARNING, 2001, 45 (01) :5-32
[6]   Identifying SNPs predictive of phenotype using random forests [J].
Bureau, A ;
Dupuis, J ;
Falls, K ;
Lunetta, KL ;
Hayward, B ;
Keith, TP ;
Van Eerdewegh, P .
GENETIC EPIDEMIOLOGY, 2005, 28 (02) :171-182
[7]   Gene selection and classification of microarray data using random forest -: art. no. 3 [J].
Díaz-Uriarte, R ;
de Andrés, SA .
BMC BIOINFORMATICS, 2006, 7 (1)
[8]  
Dickson GH, 2001, EUR J SURG ONCOL, V27, P641
[9]   Esophagogastrectomy for carcinoma of the esophagus and cardia: A comparison of findings and results after standard resection in three consecutive eight-year intervals with improved staging criteria [J].
Ellis, FH ;
Heatley, GJ ;
Krasna, MJ ;
Williamson, WA ;
Balogh, K .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1997, 113 (05) :836-846
[10]   An audit of surgical outcomes of esophageal squamous cell carcinoma [J].
Goan, Yih-Gang ;
Chang, Huang-Chou ;
Hsu, Hon-Ki ;
Chou, Yi-Pin .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2007, 31 (03) :536-544