Modeling heart rate variability by stochastic feedback

被引:12
作者
Amaral, LAN [1 ]
Goldberger, AL
Ivanov, PC
Stanley, HE
机构
[1] MIT, Dept Phys, Cambridge, MA 02139 USA
[2] Harvard Univ, Sch Med, Div Cardiovasc, Boston, MA 02215 USA
[3] Boston Univ, Ctr Polymer Studies, Boston, MA 02215 USA
[4] Boston Univ, Dept Phys, Boston, MA 02215 USA
关键词
D O I
10.1016/S0010-4655(99)00295-7
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We consider the question of how the cardiac rhythm spontaneously self-regulates and propose a new mechanism as a possible answer. We model the neuroautonomic regulation of the heart rate as a stochastic feedback system and find that the model successfully accounts for key characteristics of cardiac variability, including the 1/f power spectrum, the functional form and scaling of the distribution of variations of the interbeat intervals, and the correlations in the Fourier phases which indicate nonlinear dynamics. (C) 1999 Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:126 / 128
页数:3
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