Germline stem cell transplantation and transgenesis

被引：319

作者：

Brinster, RL ^{[1
]}

机构：

[1] Univ Penn, Sch Vet Med, Dept Anim Biol, Philadelphia, PA 19104 USA

来源：

SCIENCE | 2002年 / 296卷 / 5576期

关键词：

D O I：

10.1126/science.1071607

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The recently developed testis cell transplantation method provides a powerful approach to studying the biology of the male germline stem cell and its microenvironment, the stem cell niche. The technique also is being used to examine spermatogenic defects, correct male infertility, and generate transgenic animals.

引用

页码：2174 / 2176

页数：3

共 31 条

[1] Reconstitution of spermatogenesis from frozen spermatogonial stem cells [J].

Avarbock, MR ;

Brinster, CJ ;

Brinster, RL .

NATURE MEDICINE, 1996, 2 (06) :693-696

[2] Juvenile spermatogonial depletion (js']jsd) mutant seminiferous tubules are capable of supporting transplanted spermatogenesis [J].

Boettger-Tong, HL ;

Johnston, DS ;

Russell, LD ;

Griswold, MD ;

Bishop, CE .

BIOLOGY OF REPRODUCTION, 2000, 63 (04) :1185-1191

[3] SPERMATOGENESIS FOLLOWING MALE GERM-CELL TRANSPLANTATION [J].

BRINSTER, RL ;

ZIMMERMANN, JW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (24) :11298-11302

[4] GERMLINE TRANSMISSION OF DONOR HAPLOTYPE FOLLOWING SPERMATOGONIAL TRANSPLANTATION [J].

BRINSTER, RL ;

AVARBOCK, MR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (24) :11303-11307

[5] Distribution of type A spermatogonia in the mouse is not random [J].

Chiarini-Garcia, H ;

Hornick, JR ;

Griswold, MD ;

Russell, LD .

BIOLOGY OF REPRODUCTION, 2001, 65 (04) :1179-1185

[6] Rat spermatogenesis in mouse testis [J].

Clouthier, DE ;

Avarbock, MR ;

Maika, SD ;

Hammer, RE ;

Brinster, RL .

NATURE, 1996, 381 (6581) :418-421

[7] Stem cells in the testis [J].

De Rooij, DG .

INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 1998, 79 (02) :67-80

[8]

Dobrinski I, 2000, MOL REPROD DEV, V57, P270, DOI 10.1002/1098-2795(200011)57:3&lt

[9]

270::AID-MRD9&gt

[10]

3.0.CO

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