Zeptomol Detection Through Controlled Ultrasensitive Surface-Enhanced Raman Scattering

被引：503

作者：

Rodriguez-Lorenzo, Laura ^{[1
,2
]}

Alvarez-Puebla, Ramon A. ^{[1
,2
]}

Pastoriza-Santos, Isabel ^{[1
,2
]}

Mazzucco, Stefano ^{[3
]}

Stephan, Odile ^{[3
]}

Kociak, Mathieu ^{[3
]}

Liz-Marzan, Luis M. ^{[1
,2
]}

Javier Garcia de Abajo, F. ^{[4
,5
]}

机构：

[1] Univ Vigo, CSIC, Dept Quim Fis, Vigo 36310, Spain

[2] Univ Vigo, CSIC, Unidad Asociada, Vigo 36310, Spain

[3] Univ Paris 11, CNRS, Phys Solides Lab, UMR8502, F-91405 Orsay, France

[4] Univ Vigo, CSIC, Inst Opt, Madrid 28006, Spain

[5] Univ Vigo, CSIC, Unidad Asociada, Madrid 28006, Spain

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 13期

关键词：

HOT-SPOTS; SERS; NANOPARTICLE; SPECTROSCOPY; MOLECULES; PLASMONS;

D O I：

10.1021/ja809418t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

SERS permits identifying the nature of molecules in extremely low concentrations, but it is hindered by poor enhancement or low reproducibility. We demonstrate controllable similar to 10(10) signal amplification reaching the zeptomol detection limit for a nonresonant molecule by sandwiching the analyte between the tips of star-shaped gold nanoparticles and a planar gold surface using a simple synthetic procedure. This unprecedented control over tight-intensity amplification opens a new avenue toward high-yield, fully reproducible, SERS-based, zeptomol detection and holds promise for nonlinear optics applications at the single-particle level.

引用

页码：4616 / +

页数：5

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