Relation between amino acid composition and cellular location of proteins

被引：346

作者：

Cedano, J

Aloy, P

PerezPons, JA

Querol, E

机构：

[1] UNIV AUTONOMA BARCELONA,INST BIOL FONAMENTAL 5,E-08193 BELLATERRA,BARCELONA,SPAIN

[2] UNIV AUTONOMA BARCELONA,DEPT BIOQUIM & BIOL MOL,E-08193 BELLATERRA,BARCELONA,SPAIN

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1997年 / 266卷 / 03期

关键词：

protein location; protein prediction algorithms; amino acid composition; protein sequence analysis; biocomputing;

D O I：

10.1006/jmbi.1996.0804

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A correlation analysis of the amino acid composition and the cellular location of a protein is presented. The statistical analysis discriminates among the following five protein classes: integral membrane proteins, anchored membrane proteins, extracellular proteins, intracellular proteins and nuclear proteins. This segregation into protein classes related to their location can help researchers to design experimental work for testing hypotheses in order to find out the functionality of a reading frame in search of function. A program (ProtLock) to predict the cellular location of a protein has been designed. (C) 1997 Academic Press Limited.

引用

页码：594 / 600

页数：7

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