Thyroid hormone action and brain development

被引：267

作者：

Koibuchi, N ^{[1
]}

Chin, MW

机构：

[1] Dokkyo Univ, Sch Med, Dept Physiol, Mibu, Tochigi 3210293, Japan

[2] Eli Lilly & Co, Lilly Corp Ctr, Lilly Res Labs, Gene Regulat Res, Indianapolis, IN 46285 USA

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2000年 / 11卷 / 04期

关键词：

D O I：

10.1016/S1043-2760(00)00238-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Thyroid hormone (TH) plays a crucial role in brain development, Developing rodent cerebellum might be an excellent model for studying the molecular mechanisms of TH action in the brain because perinatal hypothyroidism greatly affects its ontogeny. Although the TH-regulated genes that play crucial roles in cerebellar development have not yet been fully characterized, recent studies have provided novel insights into TH action in brain development.

引用

页码：123 / 128

页数：6

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