Batai and Ngari viruses: M segment reassortment and association with severe febrile disease outbreaks in East Africa

被引：130

作者：

Briese, T ^{[1
]}

Bird, B

Kapoor, V

Nichol, ST

Lipkin, WI

机构：

[1] Columbia Univ, Jerome L & Dawn Greene Infect Dis Lab, Mailman Sch Publ Hlth, New York, NY 10032 USA

[2] Ctr Dis Control & Prevent, Special Pathogens Branch, Div Viral & Rickettsial Dis, Atlanta, GA 30333 USA

[3] Univ Calif Davis, Sch Vet Med, Davis, CA 95616 USA

来源：

JOURNAL OF VIROLOGY | 2006年 / 80卷 / 11期

关键词：

D O I：

10.1128/JVI.02448-05

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Ngari virus is an orthobunyavirus recently recognized as a reassortant between Bunyamwera virus and an as yet unidentified M segment donor. Analysis of M segment sequences of Batai and Ilesha viruses revealed 95% deduced amino acid identity between Batai virus and Ngari virus. These findings suggest Batai virus as the donor of Ngari virus M segment sequence. Analysis of Batai virus-related African isolates identified UgMP-6830, isolated from mosquitoes in Uganda, as an isolate of Batai virus. KV-141, isolated during a febrile disease outbreak in Sudan, was identified as another isolate of Ngari virus, emphasizing a role of this reassortant virus in severe human illness throughout East Africa.

引用

页码：5627 / 5630

页数：4

共 21 条

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