Increased left ventricular mass in obese adolescents

被引:53
作者
Friberg, P [1 ]
Allansdotter-Johnsson, Å
Ambring, A
Ahl, R
Arheden, H
Framme, J
Johansson, Å
Holmgren, D
Wåhlander, H
Marild, S
机构
[1] Univ Gothenburg, Dept Clin Physiol, Sahlgrenska Acad, Sahlgrenska Univ Hosp,Queen Silvia Childrens Hosp, Gothenburg, Sweden
[2] Univ Gothenburg, Dept Radiol, Sahlgrenska Acad, Sahlgrenska Univ Hosp,Queen Silvia Childrens Hosp, Gothenburg, Sweden
[3] Univ Gothenburg, Dept Paediat, Sahlgrenska Acad, Sahlgrenska Univ Hosp,Queen Silvia Childrens Hosp, Gothenburg, Sweden
[4] Univ Lund Hosp, Dept Clin Physiol, S-22185 Lund, Sweden
关键词
obesity; paediatrics; myocardium; magnetic resonance imaging; blood pressure;
D O I
10.1016/j.ehj.2004.03.018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims An increase of left ventricular mass (LVM) has been reported in obese adolescents in previous studies using echocardiography. The aim of our study was to determine the extent of the increase in LVM and correlation to other risk factors using cardiac magnetic resonance imaging in obese and lean adolescents. Methods and results Nineteen obese and 20 lean adolescents were recruited. Following resting blood pressure measurements and blood sampling for insulin, triglycerides, and cholesterol levels, all subjects underwent cardiac magnetic resonance examination to assess LVM. LVM adjusted for body height was 16% greater in obese compared to lean adolescents (median 66 g/m, p = 0.0042). Obese subjects had higher resting systolic blood pressures than controls (median 115 vs. 110 mmHg, p = 0.0077) and higher fasting triglyceride and insulin levels. HDL-cholesterol levels were tower in the obese group compared with the lean group. Conclusions Obese adolescents had a higher LVM than age-matched lean subjects, which correlated mainly with body mass index and systolic blood pressure. These findings add to the established cardiovascular risk profile of obese adolescents. (C) 2004 Published by Elsevier Ltd on behalf of The European Society of Cardiology.
引用
收藏
页码:987 / 992
页数:6
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