Interaction between GADD34 and kinesin superfamily, KIF3A

被引：19

作者：

Hasegawa, T ^{[1
]}

Yagi, A ^{[1
]}

Isobe, K ^{[1
]}

机构：

[1] Natl Inst Longev Sci, Dept Basic Gerontol, Aichi 4748522, Japan

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2000年 / 267卷 / 02期

关键词：

D O I：

10.1006/bbrc.1999.1991

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

GADD34 is one of a subset of proteins induced after DNA damage or cell growth arrest, To examine the function of GADD34, we used the yeast two-hybrid system to clone the protein that interacts with the murine GADD34. One cDNA clone was the C-terminal part of KIF3A gene including the tail domain. The interaction between GADD34 and KIF3A was confirmed in the NIH3T3 cells by in vivo two-hybrid analysis. We could detect that GADD34 was induced with methyl methanesulfonate; however, the mRNA induction of KIF3A was not detected, (C) 2000 Academic Press.

引用

页码：593 / 596

页数：4

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